“Lipovarin’s proprietary formula known as Metazide is so effective because it targets fat loss from so many different angles metabolism boosting, appetite suppression and thyroid support are just a few of the ways this amazing formula will help you achieve your goals.”
Is it true? Will targeting “different angles” help you lose weight faster? Maybe… or maybe not – this isn’t something that I’ve ever seen studied. There are actually very few studies on combinations of ingredients, and even fewer that demonstrate that the results are superior to single ingredients.
That said, let’s take a closer look at the Lipovarin formula.
Not surprisingly, there’s a huge focus on mood elevation in this formula. Caffeine, glucuronolactone, and taurine, all present in Lipovarin, are also present in the popular “Red Bull” energy drink. Caffeine, of course, is a well known stimulant. There’s some evidence that in high doses, taurine, an amino acid, lowers blood pressure levels in hypertensive individuals. There is no compelling evidence, however, that either taurine or glucuronolactone have any positive effect on an increased metabolic rate or weight loss in general.
What else is in Lipovarin?
1. Advantra Z (Citrus aurantium), which is standardized for something called synephrine: a “milder”, “gentler” ephedra. At one point it was thought that synephrine offered all the fat burning powers of ephedra without the jitters and potential dangers. Unfortunately,
Here’s what this PubMed abstract (Am J Cardiol. 2004 Nov 15;94(10):1359-61.) had to say about citrus aurantium…
“An extensive search of MEDLINE, EMBASE, BIOSIS, and the Cochrane Collaboration Database identified only 1 eligible randomized placebo controlled trial, which followed 20 patients for 6 weeks, demonstrated no statistically significant benefit for weight loss, and provided limited information about the safety of the herb.”
2. Metabromine (standardized for 6% theobromine): a stimulant derived from cocoa, and found in chocolate — it too may have a positive effect on mood and possibly even the metabolism — likely a result of its xanthine and biogenic-amines content.
3. Green tea extract: a beneficial and all-round helpful ingredient, Green tea exhibits powerful antioxidant activity, is active as a glucose moderator, and has even been shown to elevate metabolic rate — far beyond the level of its caffeine content. Don’t get too excited though — one study showed a 4% increase in 24-hour energy expenditure — this translates into less than 100 calories per day for most people. If you are overeating, green tea won’t help you.
4. Serotain: contains 5-HTP, dervied from Griffonia simplicifolia, a West African plant. 5-HTP is often used to treat mild depression on the premise that as a precursor to serotonin (a chemical neurotransmitter found in the brain). 5-HTP can increase serotonin levels and influence mood. There is some evidence 5-HTP may indeed have an effect on appetite, and possibly even mood, but these positive results were obtained with nearly 10 times the amount of active ingredient found in Lipovarin.
5. Rhodiola rosea: an adaptogen that has been shown to improve endurance exercise performance (Int J Sport Nutr Exerc Metab. 2004 Jun;14(3):298-307).
6. Carnitine: an amino acid which helps facilitate the burning of fatty acids (fat) in the mitochondria (the “energy furnace” of the cell). Although research on Carnitine has been inconclusive, it is generally not been found effective for anything under doses of 2,000 mg (there are 15 mg of Carnitine in Lipovarin). Carnitine may also provide some cardiovascular health benefits (a full review of Carnitine can be found here).
7. 7-keto: a metabolite of DHEA, with no apparent side effects – i.e. no conversion to testosterone or estrogen, and no effect on the sex hormones. What’s promising about 7-keto is its positive effect on thyroid hormone levels — without any adverse effects of any kind.
In quoting a recent study in his superb Fat Loss Revealed (where the control group lost 0.57% of their bodyweight, and the group on 7-keto lost 1.8% – about 6 lbs on average), Will Brinks’ says 7-keto is a potentially promising weight loss agent!
This is a promising beginning, but no more than that. More studies need to be completed to more thoroughly demonstrate 7-keto’s fat burning ability.
8. Coleus forskohlii: a cAMP regulator that may help speed intercellular processes, and possibly therefore, the metabolism. While the effects of coleus forskohlii and a corresponding positive effect on weight loss have been established in one study (Journal of Obesity Research August 2005, “Body Composition and Hormonal Adaptations Associated With Forskolin Consumption In Overweight and Obese Men“), the results were not overwhelming.
So there you have it — Lipovarin, the latest “weight loss wonder”. Despite the outrageous claims, this is actually a “better than average” product. Heck, I even experiemented with it and found it to be a great “mood elevator”, keeping me mentally focused and positive without any side effects (I could only tolerate a single capsule serving of this product. More than that did indeed make me “jittery.”)
However, while it may help you maintain an elevated mood and give you a boost of energy while dieting, don’t expect miracles from it. If you haven’t already made the appropriate changes to your diet and lifestyle, Lipovarin will do nothing for you.
For those of you have tried Lipovarin, please let me know how it worked for you!