Huperzine A
An alkaloid isolated from a Chinese moss (Huperzia serrata) that has neuroprotective and cognitive effects. Huperzine A is often added to pre-workout supplements to enhance focus/concentration.
7-Keto, 7-Keto DHEA
A metabolite of DHEA, is a steroid hormone that is produced naturally by the bodies of both men and women. A small amount of clinical data confirms 7-Keto’s positive effect on thyroid hormone levels in obese people, indicating it may offer weight loss benefits.
Guarana
A South American plant that produces berries with a high concentration (up to 7.5%) of caffeine. Guarana extracts have been used in traditional folk medicine, as well as a base for soft drinks. In North America, standardized guarana extracts are used as a “natural” source of caffeine in weight loss supplements and energy drinks.
See Paul’s review, “Guarana – Caffeine’s Fat-Burning Connection” for more information.
Glucuronolactone
A naturally-occurring metabolite of glucose. Glucuronolactone is used in energy drinks as well as some pre-workout supplements as an energy booster. It’s also sold in bulk powder form. There are no studies on glucuronolactone that validate its use for enhancing mood or energy, however – the evidence is strictly anecdotal.
GABA
GABA stands for gamma-aminobutyric acid, an inhibitory neurotransmitter derived from glutamate (an amino acid and excitatory neurotransmitter). When taken in supplemental form, GABA has a mild sedative effect that can aid relaxation and sleep. Supplemental GABA may also stimulate resting growth hormone production.
