Phendimetrazine Diet Pill Review
Phendimetrazine, a bitter, white diet pill, is used for weight loss in obesity. It belongs to a class of drugs that are believed to help control weight by decreasing appetite (also known as anorectics). Phendimetrazine diet pills are typically prescribed at a dose of 1 to 2 35mg tablets up to three times a day, taken an hour before meals.
How does Phendimetrazine work?
Phendimetrazine diet pills fall under a group of drugs that are very similar in their action to amphetamines.
Information on Phendimetrazine’s mechanism of action as it is related to weight loss is limited and unclear. The decreased appetite seen with Phendimetrazine diet pills is equally attributed to their excitatory action on the brain and to as yet unknown effects on metabolism. The end result, in either case, is decreased appetite and increased satiety. Thus, food intake is reduced and the restricted calorie consumption is speculated to result in weight loss.
Therapy with Phendimetrazine diet pills is justified when diet and exercise alone have failed to produce a weight loss of more than 0.5 kg/1 lb. week after a four week diet trial in an individual with a BMI of 30 kg/m2 (or 27 kg/m2 in the presence of other risk factors like diabetes, hypertension and hyperlipidemia).
Note: Body Mass Index is calculated as so… BMI=weight(kg)/ [height(m)2]. You can use this online BMI calculator to determine yours!
In controlled studies where Phendimetrazine diet pills were compared to a placebo, the difference in weight loss was not more than a fraction of a pound a week. Added to this low efficacy, these diet pills seem to stop working after a couple of weeks. The body gets used to their stimulatory effects and develops a tolerance. At this point, a further increase in the dose will only aggravate the adverse effects of the drug. Many other factors also seem to be related to the Phendimetrazine produced weight loss, such as the physician-investigator relationship, the population treated and the diet prescribed.
Considering all this, Phendimetrazine is not the most effective of diet pills. The indications to use this drug are very limited. It is recommended only as a short term solution (3 weeks at most) and in cases where obesity is purely related to excessive caloric intake. The safety of the drug has not been documented in pregnant women and children under 12 years. People with mild hypertension and diabetes need strict supervision of their medical practitioner should they choose to take these diet pills.
Phendimetrazine diet pills do have effects on other organ systems. Their stimulating action can cause excitation, hyperactivity and irritability. It also causes an increase in the blood pressure. Once the therapy is started the drug should not be stopped suddenly — a sudden cessation of its stimulatory effect could lead to fatigue and depression. Also occupational and recreational activities involving mechanical machinery should be avoided for the duration of the therapy.
People with symptomatic heart or blood vessel disease, hypertension, thyroid disorders, anxiety disorders, past history of drug abuse or known allergy to this class of drugs are not suitable for Phendimetrazine diet pills. Overdose of this drug is also a serious complication that requires treatment with sedatives and intravenous drugs to control hypertension.