a.k.a. “Veld Grape” – a medicinal plant native to Africa, India, and other parts of Asia. Cissus has traditionally been used to treat a variety of ailments such as bone fractures, ulcers, wounds, indigestion and asthma. Animal studies have shown Cissus extracts may have gastroprotective effects, contribute to bone health, and have antioxidant/antimicrobial activities.
Cissus quadrangularis has gained popularity in bodybuilding circles as an analgesic and palliative for weight lifting injuries. It has also been touted as a weight loss agent on the strength of two manufacturer-supported studies (Lipids Health Dis. 2007 Feb 4;6:4 and Lipids Health Dis. 2006 Sep 2;5:24). We have some questions about these studies, however, as a) weight/fat loss is typically not reported in user reviews of Cissus by bodybuilders; and b) the studies were conducted by the owner of a patent on Cissus as a weight loss agent – a potential conflict of interest. We would prefer to see independent confirmation before recommending Cissus quadrangularis as a weight loss agent.