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2-Phenethylamine

See: Phenethylamine (PEA).

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5-Methyl-7-Methoxyisoflavone

Also known as “methoxyisoflavone” or “methoxy.”   5-Methyl-7-Methoxyisoflavone is a derivative of ipriflavone touted as a non-hormonal muscle-building supplement. A 2006 study on resistance-trained men, however, failed to find any...

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3-Acetyl-7-Oxo-Dehydroepiandosterone

See 7-Keto-DHEA.

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7-Keto-DHEA

7-Keto-DHEA is an acetylated form of a DHEA metabolite (7-oxo-DHEA) used in a number of weight loss supplements.  Unlike DHEA, it cannot be converted to androgens (i.e., testosterone) or estrogens.  Several studies in humans indicate that 7-Keto-DHEA can modestly increase RMR and enhance weight/fat loss when taken in conjunction with a structured diet and exercise program.  Studies in rats have shown 7-keto may work by increasing...

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6,8-Thioctic Acid

A potent antioxidant that can increase insulin sensitivity and glucose disposal in human and animal models. Alpha-lipoic acid (ALA) is also frequently added to creatine transport formulas as research has shown it improves creatine uptake. ALA may have therapeutic applications.  For example, animal experiments have shown a combination of ALA and acetyl-l-carnitine can mitigate age-related mitochondrial decay. It may also be useful for...

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25-Deoxy-20-Hydroxyecdysone

Also known as Ponasterone A.  An ecdysteroid and analog of 20-hydroxyecdysone.  25-Deoxy-20-Hydroxyecdysone is sometimes listed as a component of standardized extracts used in bodybuilding supplements, although there is little information on what effects – if any – it has on mammals when given in isolation (FYI: one chemical supplier states it’s “inert to mammalian...

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