{"id":474,"date":"2011-03-28T01:15:48","date_gmt":"2011-03-28T01:15:48","guid":{"rendered":"http:\/\/vitamins.ultimatefatburner.com\/?p=474"},"modified":"2016-01-04T15:17:06","modified_gmt":"2016-01-04T20:17:06","slug":"potassium-iodide-review","status":"publish","type":"post","link":"https:\/\/www.ultimatefatburner.com\/vitamins\/potassium-iodide-review.html","title":{"rendered":"Potassium Iodide; Protect against Radioactive Iodine &#038; More!"},"content":{"rendered":"<h1>What is Potassium Iodide?<\/h1>\n<p><strong>Potassium iodide (KI)<\/strong> is a salt of the essential mineral iodine. Your body needs iodine to synthesize the hormones thyroxine (T<sub>4<\/sub>) and triiodothyronine (T<sub>3<\/sub>). These two hormones are vitally important for normal development, growth and metabolism.<\/p>\n<p>T<sub>4<\/sub> and T<sub>3<\/sub> are produced by the thyroid gland: a small, butterfly-shaped organ located in the neck. <a href=\"http:\/\/www.vivo.colostate.edu\/hbooks\/pathphys\/endocrine\/thyroid\/anatomy.html\" target=\"_blank\" rel=\"noopener\">These hormones are made by specialized structures called &#8220;thyroid follicles,&#8221;<\/a> and then released into the bloodstream.<\/p>\n<h2>What is It Used For?<\/h2>\n<p>KI is used as a nutritional supplement for both humans and animals. It&#8217;s routinely added to livestock feeds, fortified foods, multivitamin formulas and iodized salt.<\/p>\n<p><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2626287\/pdf\/16175826.pdf\" target=\"_blank\" rel=\"noopener\">Iodine deficiency is a serious public health problem in many parts of the world<\/a>, so potassium iodide supplementation\u2014particularly in the form of iodized salt\u2014is vital for preventing iodine deficiency disorders (IDDs). IDDs are responsible for widespread health problems, including <a href=\"http:\/\/www.ign.org\/index.cfm\" target=\"_blank\" rel=\"noopener\">neurological and cognitive damage<\/a>, impaired growth, goiter and hypothyroidism.<\/p>\n<p>KI has pharmaceutical uses too. It&#8217;s used for medical imaging, as an emergency treatment for hyperthyroidism (&#8220;<a href=\"http:\/\/emedicine.medscape.com\/article\/925147-treatment?cc=aHR0cDovL2VtZWRpY2luZS5tZWRzY2FwZS5jb20vYXJ0aWNsZS85MjUxNDctdHJlYXRtZW50&amp;cookieCheck=1\" target=\"_blank\" rel=\"noopener\">thyroid storm<\/a>&#8220;), as an <a href=\"https:\/\/healthy.kaiserpermanente.org\/health\/care\/consumer\/health-wellness\/drugs-and-natural-medicines\/drug-encyclopedia\/medicine-information\/!ut\/p\/a1\/fc9Nb4JAEAbg3-KBY90XV3DpbdXULhQ_ImntXhq0K5LwlXWR-O8LlvZUO7eZPPNmhkiyI7KIL2kSm7Qs4qzrpfsRQaymU5sDtnAg1j5bzhkbYUbJG_GJTLJyf8PvJ2OqRwsWPnWdqOJwfahKbTJlLBDZzcSc7MYOPHgd58WesoRIrY5KKz2sdZvym9E0zbDOTJrHRh1js6910ZpDmVu4pCbO0-L8V8ipPBuyu7vcniz__wo9ePK332A19hhEOHueiWUALCY9WHMIFsKxwakL4UY0mIRLG4txD0DF5pawWLtobRAFr15AgdEPuFMcpMrZlWaXl-NWpIIPBl8YcYsY\/dl5\/d5\/L2dBISEvZ0FBIS9nQSEh\/\" target=\"_blank\" rel=\"noopener\">expectorant<\/a>, and as a treatment for <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/14660263\" target=\"_blank\" rel=\"noopener\">cutaneous sporotrichosis<\/a> (a fungal skin infection).<\/p>\n<p>Just as importantly, KI can be used to protect your thyroid gland from exposure to the radioactive iodine released during a nuclear accident or emergency.<\/p>\n<p>Serious nuclear power plant accidents, such as <a href=\"http:\/\/www.who.int\/ionizing_radiation\/chernobyl\/who_chernobyl_report_2006.pdf\" target=\"_blank\" rel=\"noopener\">Chernobyl<\/a> (Ukraine, 1986), <a href=\"http:\/\/www.nrc.gov\/reading-rm\/doc-collections\/fact-sheets\/3mile-isle.html\" target=\"_blank\" rel=\"noopener\">Three Mile Island<\/a> (US, 1979) and <a href=\"https:\/\/www.iaea.org\/newscenter\/news\/fukushima-nuclear-accident-update-log-51\" target=\"_blank\" rel=\"noopener\">Fukushima<\/a> (Japan, 2011), typically release gaseous iodine-131 (<sup>131<\/sup>I) into the atmosphere, where it can drift for miles beyond the point of origin.<\/p>\n<p>Although the half-life of <sup>131<\/sup>I is relatively short (~8 days), once inhaled or ingested (via contaminated food), it can be taken up by the thyroid gland, just like stable (non-radioactive) iodine is.<\/p>\n<p>The resulting radiation damage <a href=\"http:\/\/www.health.harvard.edu\/blog\/thyroid-cancer-a-hazard-from-radioactive-iodine-emitted-by-japans-failing-nuclear-power-plants-201103141867\" target=\"_blank\" rel=\"noopener\">dramatically increases the risk of developing thyroid disease\u2014including cancer<\/a>.<\/p>\n<p><a href=\"http:\/\/www.buffalo.edu\/news\/faculty-experts.html\" target=\"_blank\" rel=\"noopener\">And the risk to infants and children is even higher than that of adults.<\/a><\/p>\n<h3>How Does It Protect from Radioactive Iodine?<\/h3>\n<p>How does KI protect the thyroid from <sup>131<\/sup>I?<\/p>\n<p>FDA-approved supplements provide KI in a dose (130mg) that provides iodine far in excess of the RDA (150ug for adults). <a href=\"http:\/\/www.fda.gov\/Drugs\/EmergencyPreparedness\/BioterrorismandDrugPreparedness\/ucm072265.htm\" target=\"_blank\" rel=\"noopener\">This floods the thyroid with stable iodine, and effectively blocks uptake of the radioactive isotope.<\/a><\/p>\n<p>The unabsorbed <sup>131<\/sup>I is then rapidly excreted in urine. While KI intake does not protect against exposure to other radionuclides (such as strontium-90, plutonium-239 or cesium-137), it can help prevent one of the best-known threats to health caused by nuclear fallout.<\/p>\n<p>Taking protective doses of KI is not without risk, however, which is why strict guidelines for usage have been developed by <a href=\"http:\/\/www.fda.gov\/downloads\/Drugs\/GuidanceComplianceRegulatoryInformation\/Guidances\/UCM080542.pdf\" target=\"_blank\" rel=\"noopener\">the US FDA<\/a> and other agencies throughout the world (<a href=\"http:\/\/www.who.int\/ionizing_radiation\/pub_meet\/Iodine_Prophylaxis_guide.pdf\" target=\"_blank\" rel=\"noopener\">such as WHO<\/a>).<\/p>\n<p><a href=\"http:\/\/emergency.cdc.gov\/radiation\/ki.asp#med\" target=\"_blank\" rel=\"noopener\">According to the US Centers for Disease Control (CDC)<\/a>, taking KI could be harmful to people with allergies to iodine or who have certain skin disorders. In addition, those with pre-existing thyroid disease, or who are taking specific prescription drugs (<a href=\"http:\/\/umm.edu\/health\/medical\/altmed\/supplement\/iodine\" target=\"_blank\" rel=\"noopener\">lithium, warfarin\/coumadin or anti-thyroid medications<\/a>) should take it only under medical supervision.<\/p>\n<p>KI can cause side effects in healthy people too, such as upset stomach, skin rash and\/or inflamed salivary glands. While large doses of KI are safe when taken over the recommended period of time (14 days), longer-term use can induce hypothyroidism.<\/p>\n<p>In summary: <strong>thyroid-protective doses of KI should be taken only when the radiation exposure warrants it, for no more than the prescribed period of time and in age-appropriate amounts.<\/strong><\/p>\n<h3>Dosing Guidelines<\/h3>\n<p><a href=\"http:\/\/www.fda.gov\/Drugs\/EmergencyPreparedness\/BioterrorismandDrugPreparedness\/ucm072265.htm#What%20dosages\" target=\"_blank\" rel=\"noopener\">These are the dosing guidelines, according to the FDA:<\/a><\/p>\n<p align=\"center\"><strong>* * * * * * * * * * * * * * * * * * * *<\/strong><\/p>\n<table border=\"1\" summary=\"Dosing of potassium iodide for thyroid blocking\">\n<tbody style=\"font-size: 14px; line-height: 16px; text-align: center;\">\n<tr>\n<td bgcolor=\"#cccccc\"><\/td>\n<th style=\"padding: 5px 0;\" scope=\"col\" bgcolor=\"#cccccc\">Predicted Thyroid gland exposure (cGy)<\/th>\n<th scope=\"col\" bgcolor=\"#cccccc\">KI dose (mg)<\/th>\n<th scope=\"col\" bgcolor=\"#cccccc\">Number or fraction of 130 mg tablets<\/th>\n<th scope=\"col\" bgcolor=\"#cccccc\">Number or fraction of 65 mg tablets<\/th>\n<th scope=\"col\" bgcolor=\"#cccccc\">Milliliters (mL) of oral solution, 65\u00a0mg\/mL***<\/th>\n<\/tr>\n<tr>\n<th style=\"padding: 5px 0;\" scope=\"row\">Adults over<br \/>\n40 years<\/th>\n<td><span style=\"text-decoration: underline;\">&gt;<\/span> 500<\/td>\n<td>130<\/td>\n<td>1<\/td>\n<td>2<\/td>\n<td>2 mL<\/td>\n<\/tr>\n<tr>\n<th style=\"padding: 5px 0;\" scope=\"row\">Adults over<br \/>\n18 through 40 years<\/th>\n<td><span style=\"text-decoration: underline;\">&gt;<\/span> 10<\/td>\n<td>130<\/td>\n<td>1<\/td>\n<td>2<\/td>\n<td>2 mL<\/td>\n<\/tr>\n<tr>\n<th style=\"padding: 5px 0;\" scope=\"row\">Pregnant or<br \/>\nLactating Women<\/th>\n<td><span style=\"text-decoration: underline;\">&gt;<\/span>\u00a05<\/td>\n<td>130<\/td>\n<td>1<\/td>\n<td>2<\/td>\n<td>2 mL<\/td>\n<\/tr>\n<tr>\n<th style=\"padding: 5px 0;\" scope=\"row\">Adolescents,<br \/>\n12 through<br \/>\n18 years*<\/th>\n<td><span style=\"text-decoration: underline;\">&gt;<\/span>\u00a05<\/td>\n<td>65<\/td>\n<td>\u00bd<\/td>\n<td>1<\/td>\n<td>1\u00a0mL<\/td>\n<\/tr>\n<tr>\n<th style=\"padding: 5px 0;\" scope=\"row\">Children over<br \/>\n3 years through 12 years<\/th>\n<td><span style=\"text-decoration: underline;\">&gt;<\/span> 5<\/td>\n<td>65<\/td>\n<td>\u00bd<\/td>\n<td>1<\/td>\n<td>1 mL<\/td>\n<\/tr>\n<tr>\n<th style=\"padding: 5px 0;\">Children 1<br \/>\nmonth through 3 years<\/th>\n<td><span style=\"text-decoration: underline;\">&gt;<\/span> 5<\/td>\n<td>32<\/td>\n<td>Use KI oral solution**<\/td>\n<td>\u00bd<\/td>\n<td>0.5\u00a0mL<\/td>\n<\/tr>\n<tr>\n<th style=\"padding: 5px 0;\" scope=\"row\">Infants birth through 1<br \/>\nmonth<\/th>\n<td><span style=\"text-decoration: underline;\">&gt;<\/span> 5<\/td>\n<td>16<\/td>\n<td>Use KI oral solution**<\/td>\n<td>Use KI oral solution**<\/td>\n<td>0.25\u00a0mL<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>* Adolescents approaching adult size (&gt; 150 lbs) should receive the full adult dose (130 mg)<\/p>\n<p>** Potassium iodide oral solution is supplied in 1 oz (30 mL) bottles with a dropper marked for 1, 0.5, and 0.25 mL dosing. each mL contains 65 mg potassium iodide.<\/p>\n<p>*** See the <a href=\"http:\/\/www.fda.gov\/Drugs\/EmergencyPreparedness\/BioterrorismandDrugPreparedness\/ucm072248.htm\" target=\"_blank\" rel=\"noopener\">Home Preparation Procedure for Emergency Administration of Potassium Iodide Tablets to Infants and Small Children<\/a>.<\/p>\n<p align=\"center\"><strong>* * * * * * * * * * * * * * * * * * * *<\/strong><\/p>\n<p>FDA-approved brands of protective KI supplements are <a href=\"http:\/\/www.anbex.com\/\" target=\"_blank\" rel=\"noopener\">Iosat<\/a>, <a href=\"https:\/\/www.thyrosafe.com\/faq\/\" target=\"_blank\" rel=\"noopener\">ThyroSafe<\/a> and ThyroShield.<\/p>\n<blockquote>\n<p align=\"center\"><strong>I Live in North America. Should I Be Taking KI to Protect Myself From the Fukushima Reactor Fallout?<\/strong><\/p>\n<p align=\"left\"><a href=\"http:\/\/www.nbcnews.com\/id\/42135438\/ns\/health-health_care\/\" target=\"_blank\" rel=\"noopener\">Various media outlets<\/a> have reported a surge in KI purchases in the continental US&#8230; as well as an increase in the number of KI-related calls to poison control centers. Although the Fukushima accident is serious and has yet to be resolved, there is little reason to be concerned for your own health\/safety. Given the very long distance (over 5,000 miles to the coast of California) and relatively short half-life of <sup>131<\/sup>I, it&#8217;s highly unlikely that harmful levels will reach the West Coast or other areas in the continental United States.<\/p>\n<p align=\"left\">Public health authorities in the US <a href=\"http:\/\/www.hc-sc.gc.ca\/hc-ps\/ed-ud\/respond\/nuclea\/potassium-eng.php\" target=\"_blank\" rel=\"noopener\">and Canada<\/a> strongly recommend that consumers NOT take KI at this time.<\/p>\n<p align=\"left\">People interested in general emergency preparedness should avoid buying (useless) homeopathic preparations and <a href=\"http:\/\/money.cnn.com\/2011\/03\/18\/news\/economy\/CDC_iodide_radiation_advisory\/index.htm\" target=\"_blank\" rel=\"noopener\">potentially fake KI products from unreliable online marketers<\/a>.<\/p>\n<\/blockquote>\n<p>For general health and disease-prevention, most people living in iodine-sufficient countries will not need to take KI (or any other standalone iodine supplement). However, a product supplying the RDA for iodine may be needed for those on sodium-restricted diets lacking in iodine-rich foods (such as <a href=\"http:\/\/web.archive.org\/web\/20100902065644\/http:\/\/www.jacn.org:80\/cgi\/content\/full\/25\/1\/1\" target=\"_blank\" rel=\"noopener\">milk, eggs, seafood and seaweed<\/a>) or other fortified, functional food products.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>What is Potassium Iodide? Potassium iodide (KI) is a salt of the essential mineral iodine. Your body needs iodine to synthesize the hormones thyroxine (T4) and triiodothyronine (T3). [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":1349,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[19],"tags":[130],"_links":{"self":[{"href":"https:\/\/www.ultimatefatburner.com\/vitamins\/wp-json\/wp\/v2\/posts\/474"}],"collection":[{"href":"https:\/\/www.ultimatefatburner.com\/vitamins\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.ultimatefatburner.com\/vitamins\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.ultimatefatburner.com\/vitamins\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ultimatefatburner.com\/vitamins\/wp-json\/wp\/v2\/comments?post=474"}],"version-history":[{"count":4,"href":"https:\/\/www.ultimatefatburner.com\/vitamins\/wp-json\/wp\/v2\/posts\/474\/revisions"}],"predecessor-version":[{"id":1350,"href":"https:\/\/www.ultimatefatburner.com\/vitamins\/wp-json\/wp\/v2\/posts\/474\/revisions\/1350"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.ultimatefatburner.com\/vitamins\/wp-json\/wp\/v2\/media\/1349"}],"wp:attachment":[{"href":"https:\/\/www.ultimatefatburner.com\/vitamins\/wp-json\/wp\/v2\/media?parent=474"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.ultimatefatburner.com\/vitamins\/wp-json\/wp\/v2\/categories?post=474"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.ultimatefatburner.com\/vitamins\/wp-json\/wp\/v2\/tags?post=474"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}