{"id":258,"date":"2009-03-19T07:07:33","date_gmt":"2009-03-19T14:07:33","guid":{"rendered":"http:\/\/glossary.ultimatefatburner.com\/alphalipoic-acid.php"},"modified":"2015-02-13T08:30:39","modified_gmt":"2015-02-13T13:30:39","slug":"alphalipoic-acid","status":"publish","type":"post","link":"https:\/\/www.ultimatefatburner.com\/glossary\/alphalipoic-acid\/","title":{"rendered":"Alpha-Lipoic Acid"},"content":{"rendered":"<p>A\u00a0potent antioxidant that can increase insulin sensitivity and glucose disposal in <a href=\"http:\/\/www.hormones.gr\/158\/article\/article.html\" target=\"_blank\" rel=\"noopener\">human<\/a> and <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/15913551?ordinalpos=3&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum\" target=\"_blank\" rel=\"noopener\">animal<\/a> models. Alpha-lipoic acid (ALA) is also frequently added to creatine transport formulas as research has shown it improves <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/14669930\" target=\"_blank\" rel=\"noopener\">creatine uptake<\/a>.<\/p>\n<p>ALA may have therapeutic applications.\u00a0 For example, animal experiments have shown a combination of ALA and acetyl-l-carnitine can <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18846423\" target=\"_blank\" rel=\"noopener\">mitigate age-related mitochondrial decay<\/a>. It may also be useful for <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/19019027\" target=\"_blank\" rel=\"noopener\">treating the complications of diabetes<\/a>; as well as <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18537699\" target=\"_blank\" rel=\"noopener\">other CNS-related diseases (i.e., Alzheimer&#8217;s and multiple sclerosis)<\/a>.<\/p>\n<p>Synthetic alpha-lipoic acid is a racemic mixture consisting of two enantiomeric, &#8220;R&#8221; and &#8220;S&#8221; forms.\u00a0 Only the R form is biologically significant.\u00a0 Thus, better quality supplements provide this form exclusively (R-alpha-lipoic acid or K-R-alpha-lipoic acid &#8211; the potassium salt).<\/p>\n<p>Alpha-lipoic acid\u00a0is also\u00a0known as thioctic acid or 6,8-thioctic acid.<\/p>\n<p>See Paul&#8217;s article, &#8220;<a href=\"http:\/\/www.ultimatefatburner.com\/alpha-lipoic-acid.html\" target=\"_blank\">Alpha Lipoic Acid Reviewed: Potent Antioxidant And Blood Sugar Regulator<\/a>&#8221; &#8211; as well as the <a href=\"http:\/\/lpi.oregonstate.edu\/infocenter\/othernuts\/la\/\" target=\"_blank\" rel=\"noopener\">Linus Pauling Institute Micronutrient Center for more information<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A\u00a0potent antioxidant that can increase insulin sensitivity and glucose disposal in human and animal models. Alpha-lipoic acid (ALA) is also frequently added to creatine transport formulas as research [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[4],"tags":[87,97,123,350,468,555,664],"_links":{"self":[{"href":"https:\/\/www.ultimatefatburner.com\/glossary\/wp-json\/wp\/v2\/posts\/258"}],"collection":[{"href":"https:\/\/www.ultimatefatburner.com\/glossary\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.ultimatefatburner.com\/glossary\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.ultimatefatburner.com\/glossary\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ultimatefatburner.com\/glossary\/wp-json\/wp\/v2\/comments?post=258"}],"version-history":[{"count":0,"href":"https:\/\/www.ultimatefatburner.com\/glossary\/wp-json\/wp\/v2\/posts\/258\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.ultimatefatburner.com\/glossary\/wp-json\/wp\/v2\/media?parent=258"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.ultimatefatburner.com\/glossary\/wp-json\/wp\/v2\/categories?post=258"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.ultimatefatburner.com\/glossary\/wp-json\/wp\/v2\/tags?post=258"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}