{"id":182,"date":"2009-02-12T07:34:28","date_gmt":"2009-02-12T14:34:28","guid":{"rendered":"http:\/\/glossary.ultimatefatburner.com\/dmae-dimethylaminoethanol.php"},"modified":"2015-02-14T17:30:32","modified_gmt":"2015-02-14T22:30:32","slug":"dmae-dimethylaminoethanol","status":"publish","type":"post","link":"https:\/\/www.ultimatefatburner.com\/glossary\/dmae-dimethylaminoethanol\/","title":{"rendered":"DMAE (Dimethylaminoethanol)"},"content":{"rendered":"<p>Dimethylaminoethanol is an <a href=\"http:\/\/en.wikipedia.org\/wiki\/Dimethylethanolamine\" target=\"_blank\" rel=\"noopener\">industrial chemical<\/a>\u00a0and dietary supplement\u00a0 <a href=\"http:\/\/www.lef.org\/magazine\/2004\/11\/aas\/Page-01\" target=\"_blank\" rel=\"noopener\">used for memory\/cognitive enhancement<\/a>.\u00a0 DMAE is an analog of the essential nutrient\u00a0choline, and is\u00a0thought to increase levels of the\u00a0neurotransmitter acetylcholine.\u00a0Nonetheless, research on DMAE as a treatment for cognitive\/neurological disorders is conflicting, and\u00a0often does not support the claims made for it.<\/p>\n<p>Research has shown that DMAE is actually <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/11460263\" target=\"_blank\" rel=\"noopener\">an inhibitor of choline uptake and metabolism<\/a>\u00a0and is a <a href=\"http:\/\/www.fasebj.org\/content\/16\/6\/619.full\" target=\"_blank\" rel=\"noopener\">potential teratogen<\/a>.\u00a0 It is also used extensively in <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/15675889\" target=\"_blank\" rel=\"noopener\">&#8220;cosmeceutical&#8221; formulas to reduce wrinkles<\/a>, but short-term improvements in skin firmness may come at the expense of overall skin health, as DMAE is <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17940822\" target=\"_blank\" rel=\"noopener\">toxic to skin fibroblasts<\/a> and <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17300230\" target=\"_blank\" rel=\"noopener\">induces extensive vacuolization damage<\/a>.\u00a0<\/p>\n<p>There is still much that is unknown about DMAE metabolism. A toxicological review\u00a0conducted by the National Institute of Environmental Health Sciences (NIEHS) has recommended that further research be performed to address <em>&#8220;&#8230;data gaps with special attention to pharmacokinetics and the influence of dietary choline.&#8221;<\/em><\/p>\n<p>DMAE may be\u00a0listed\u00a0on supplement labels\u00a0by an older name, &#8220;Deanol.&#8221;\u00a0 DMAE bitartrate (or Deanol Bitartrate) is the most commonly used supplement form.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Dimethylaminoethanol is an industrial chemical\u00a0and dietary supplement\u00a0 used for memory\/cognitive enhancement.\u00a0 DMAE is an analog of the essential nutrient\u00a0choline, and is\u00a0thought to increase levels of the\u00a0neurotransmitter acetylcholine.\u00a0Nonetheless, research [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[4],"tags":[67,257,287,306,363,372,387,669,878,904,919,994],"_links":{"self":[{"href":"https:\/\/www.ultimatefatburner.com\/glossary\/wp-json\/wp\/v2\/posts\/182"}],"collection":[{"href":"https:\/\/www.ultimatefatburner.com\/glossary\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.ultimatefatburner.com\/glossary\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.ultimatefatburner.com\/glossary\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ultimatefatburner.com\/glossary\/wp-json\/wp\/v2\/comments?post=182"}],"version-history":[{"count":0,"href":"https:\/\/www.ultimatefatburner.com\/glossary\/wp-json\/wp\/v2\/posts\/182\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.ultimatefatburner.com\/glossary\/wp-json\/wp\/v2\/media?parent=182"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.ultimatefatburner.com\/glossary\/wp-json\/wp\/v2\/categories?post=182"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.ultimatefatburner.com\/glossary\/wp-json\/wp\/v2\/tags?post=182"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}