{"id":783,"date":"2010-07-15T22:40:59","date_gmt":"2010-07-15T22:40:59","guid":{"rendered":"http:\/\/bodybuilding.ultimatefatburner.com\/?p=783"},"modified":"2015-12-07T11:41:29","modified_gmt":"2015-12-07T16:41:29","slug":"usp-labs-prime-review","status":"publish","type":"post","link":"https:\/\/www.ultimatefatburner.com\/bodybuilding\/usp-labs-prime-review.html","title":{"rendered":"Review: USP Labs Prime &#8211; The Ultimate Muscle Pill?"},"content":{"rendered":"<p>&#8220;<em>&#8230;You see, there are tens of thousands of natural herbs found around the world&#8230;<\/em><\/p>\n<p><em>And, wouldn&#8217;t it make sense that some of these herbs would work with your body \u2013 not against it &#8211; to help your efforts in the gym? Of course it would\u2026<\/em><\/p>\n<p><em>While many companies have tried in the past and failed, USPlabs has quickly garnered a reputation for producing effective products that are based off herbs, not harsh, synthetic pro-hormones.<\/em><\/p>\n<p><em>To show you the power of the right extract, over 50% of all drugs used clinically are either natural products (i.e. obtained from plants, microorganisms and some animal sources) or are derivatives thereof !<\/em>&#8221;<\/p>\n<p>Actually, no, it wouldn&#8217;t make sense. While it&#8217;s quite true that a large number of pharmaceuticals are natural products (or are derived from natural products); it&#8217;s also true that those drugs are&#8230; well, drugs. And\u2014natural or no\u2014drugs can have adverse effects&#8230; sometimes serious ones. &#8220;Natural&#8221; does not mean &#8220;safe&#8221; by any means.<\/p>\n<p>If an orally-available compound (or combination of compounds) is capable of exerting profound, drug-like effects on skeletal muscle (like those nassssssty prohormones, my precious), then it&#8217;s extremely likely that\u2014yes\u2014there will be side effects&#8230; particularly when the doses are not tightly regulated (as with prescription drugs), but are merely &#8220;recommended.&#8221;<\/p>\n<p>In other words, 100% safe n&#8217; &#8220;natural&#8221; + effects on a par with prohormones = pipe dream.<\/p>\n<p>So\u2014as a marketing pitch\u2014the above is a nice try, but it&#8217;s logic FAIL, I&#8217;m afraid. Beyond that, this account raises a few questions. For example, with all those &#8220;tens of thousands of natural herbs&#8221; out there, what led USP Labs to this particular combination? What&#8217;s special about the ingredients in Prime, anyway?<\/p>\n<h3>The Ingredients in Prime<\/h3>\n<p>We can take a stab at answering these questions by examining the label:<\/p>\n<blockquote><p><strong>PrimeBlend (Proprietary Blend) 800mg<\/strong><br \/>\nTribulus Aquaticus), (Stem And Leaf), Chebula Myrobalan (Bean))<\/p><\/blockquote>\n<p>Now before we continue, there&#8217;s one thing about Prime that I like, and want to draw attention to: it&#8217;s simple. There are only two ingredients, vs. a &#8220;kitchen sink-full&#8221;, like so many other popular commercial formulations. This holds true for other USP Labs products too, such as <a href=\"https:\/\/www.ultimatefatburner.com\/bodybuilding\/Jacked.html\">Jacked<\/a>, <a href=\"https:\/\/www.ultimatefatburner.com\/bodybuilding\/anabolic-pump-review.html\">P-Slin, Anabolic Pump<\/a> and the company&#8217;s latest, &#8220;Pink Magic.&#8221; So props to USP Labs for bucking a pernicious marketing trend&#8230; and (apparently) experiencing success.<\/p>\n<p>That being said, however, USP Labs appears to be falling prey to another trend: novelty for the sake of novelty.<\/p>\n<p>While earlier supps (such as P-Slin and Anabolic Pump) had plausible mechanisms and some research behind them, Prime rests on shakier ground.<\/p>\n<p>For example, let&#8217;s start with the primary ingredient: Tribulus aquaticus.<\/p>\n<p>Exactly what is it? What sort of science is behind it?<\/p>\n<p>I searched for information but found next to nothing\u2014so I put the question to Dr. Warren L. Wagner, the Chair and Curator of Pacific Botany with the Smithsonian Institute. Dr. Wagner was kind enough to send me the following response:<\/p>\n<blockquote><p>&#8220;Tribulus aquaticus is apparently an invalid name (means never validly published into scientific literature). I don&#8217;t know if it is known what the names applies too, but one of our research databases indicates it applies to Tribulus terristris&#8230;&#8221;<\/p><\/blockquote>\n<p>Obviously, neither I nor Dr. Wagner can make any sort of definitive ID on this ingredient, in the absence of actually testing the source material. Thus it&#8217;s destined to remain a mystery\u2014at least for the present. While wholesalers are clearly marketing something by this name, it appears that there&#8217;s no such thing as &#8220;Tribulus aquaticus&#8221; in any formal, scientific sense.<\/p>\n<p>Make of it what you will. If &#8220;Tribulus aquaticus&#8221; really is Tribulus terrestris, however, then I&#8217;m not too hopeful <a href=\"https:\/\/www.ultimatefatburner.com\/bodybuilding\/tribulus-review.html\">&#8220;Trib&#8221; may improve libido<\/a>, but time has demonstrated that there&#8217;s just not a whole lot more to it. I&#8217;d be willing to go out on a limb and suggest that it\u2014like other adaptogenic plant extracts\u2014may have something to offer w\/respect to recovery from physical stress. But there&#8217;s precious little (reliable) evidence that Trib is a major muscle builder.<\/p>\n<p>What about the second ingredient?<\/p>\n<p><em>Terminalia chebula<\/em> (aka Myrobalan; Harakiri) is an Asian tree that produces small, nut-like fruits that are used for both food and medicine. <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/20480055\" target=\"_blank\" rel=\"noopener\">The fruits have antibacterial activity<\/a>, and are an integral part of <a href=\"https:\/\/www.mskcc.org\/cancer-care\/herb\/triphala\" target=\"_blank\" rel=\"noopener\">an Ayurvedic blend (Triphala) used to treat a range of diseases, from constipation to tuberculosis<\/a>. T. chebula itself has been shown to have <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18058598\" target=\"_blank\" rel=\"noopener\">anti-diabetic<\/a>,<a href=\"http:\/\/www.biomedcentral.com\/1472-6882\/6\/17\" target=\"_blank\" rel=\"noopener\"> renoprotective<\/a> and <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16634329\" target=\"_blank\" rel=\"noopener\">hepatoprotecitve<\/a> effects in animal experiments, although controlled human clinical trials are lacking.<\/p>\n<h3>The Bottom Line<\/h3>\n<p>So there you have it. For the record, I&#8217;m having a tough time seeing any justification for Prime&#8217;s claimed effects on muscle growth or strength. I suppose it miiiiiiiight help with stress and recovery&#8230; maybe&#8230; but as far as the science goes, there&#8217;s no &#8220;there&#8221; there.<\/p>\n<p>Ok, to be fair, when it comes to supplement compounds\u2014particularly those derived from traditional medicinal plants\u2014the science isn&#8217;t always complete. And Prime certainly has its fans: while the feedback is mixed, the overall trend <strong>is<\/strong> positive.<\/p>\n<p>So to help me arrive at a verdict, I bought <strong>two<\/strong> bottles, and decided to give it a try myself. After all, if it&#8217;s non-hormonal and non-androgenic, there was no reason to think\u2014if it worked at all\u2014that it wouldn&#8217;t work for me, too.<\/p>\n<p>Except it didn&#8217;t.<\/p>\n<p>I took the full, recommended dose of 6 caps\/day (which should have been quite sufficient for a lightweight like me) but felt nada: no unusual strength increases, no noticeable improvement in recovery time, no obvious boost in stamina&#8230; nothing.<\/p>\n<p>On the flip side, there were no side effects either\u2014although I might have welcomed some, if for no other reason than to convince me that Prime was more than just an herbal placebo.<\/p>\n<p>So what&#8217;s my final word?<\/p>\n<p>Either I&#8217;m a &#8220;non-responder&#8221; (to use the term being bandied around on the boards), or else there wasn&#8217;t much there for me to respond to, to begin with.<\/p>\n<p>I report, you decide.<\/p>\n<p>It&#8217;s safe to say that I&#8217;m pretty unimpressed with Prime\u2014at least as a standalone supplement. But then again, that&#8217;s pretty much what I would say about most of the herbal concoctions currently pushed as T-boosters or muscle-builders.<\/p>\n<p>Sure, there are a few herbals that appear to be useful adjuncts to a supplement stack, such as <a href=\"https:\/\/www.ultimatefatburner.com\/glossary\/cissus-quadrangularis\/\">Cissus<\/a> for injuries, <a href=\"https:\/\/www.ultimatefatburner.com\/vitamins\/rhodiola-rosea-review.html\">Rhodiola<\/a> for stress, <a href=\"https:\/\/www.ultimatefatburner.com\/glossary\/horny-goat-weed\/\">Horny Goat Weed<\/a> for libido, etc., but I&#8217;ve yet to find an herbal blend that produces solid, documented mass or strength gains; and Prime is apparently no exception.<\/p>\n<table cellspacing=\"0\">\n<tbody>\n<tr>\n<td class=\"rating\" colspan=\"2\">Summary of USPLabs Prime<\/td>\n<\/tr>\n<tr>\n<td class=\"thumbUp\"><\/td>\n<td>\n<ul class=\"pro\">\n<li>User feedback trends positive.<\/li>\n<li>Probably safe for short-term use.<\/li>\n<li>Limited number of ingredients.<\/li>\n<\/ul>\n<\/td>\n<\/tr>\n<tr>\n<td class=\"thumbDown\"><\/td>\n<td>\n<ul class=\"con\">\n<li>&#8220;Tribulus aquaticus&#8221; not properly identified.<\/li>\n<li>Limited research on ingredients.<\/li>\n<li>Available research does not support claims.<\/li>\n<\/ul>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"excerpt":{"rendered":"<p>&#8220;&#8230;You see, there are tens of thousands of natural herbs found around the world&#8230; And, wouldn&#8217;t it make sense that some of these herbs would work with your [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[4,27],"tags":[161],"_links":{"self":[{"href":"https:\/\/www.ultimatefatburner.com\/bodybuilding\/wp-json\/wp\/v2\/posts\/783"}],"collection":[{"href":"https:\/\/www.ultimatefatburner.com\/bodybuilding\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.ultimatefatburner.com\/bodybuilding\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.ultimatefatburner.com\/bodybuilding\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ultimatefatburner.com\/bodybuilding\/wp-json\/wp\/v2\/comments?post=783"}],"version-history":[{"count":5,"href":"https:\/\/www.ultimatefatburner.com\/bodybuilding\/wp-json\/wp\/v2\/posts\/783\/revisions"}],"predecessor-version":[{"id":2785,"href":"https:\/\/www.ultimatefatburner.com\/bodybuilding\/wp-json\/wp\/v2\/posts\/783\/revisions\/2785"}],"wp:attachment":[{"href":"https:\/\/www.ultimatefatburner.com\/bodybuilding\/wp-json\/wp\/v2\/media?parent=783"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.ultimatefatburner.com\/bodybuilding\/wp-json\/wp\/v2\/categories?post=783"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.ultimatefatburner.com\/bodybuilding\/wp-json\/wp\/v2\/tags?post=783"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}