{"id":63,"date":"2008-11-10T02:54:14","date_gmt":"2008-11-10T02:54:14","guid":{"rendered":"http:\/\/bodybuilding.ultimatefatburner.com\/?p=63"},"modified":"2015-12-03T11:12:40","modified_gmt":"2015-12-03T16:12:40","slug":"all-american-glutamine-elite","status":"publish","type":"post","link":"https:\/\/www.ultimatefatburner.com\/bodybuilding\/all-american-glutamine-elite.html","title":{"rendered":"Review: All American EFX Liquid Glutamine Elite"},"content":{"rendered":"<p><strong>Note: Glutamine Elite is discontinued.<\/strong><\/p>\n<p><em>&#8220;Lighting Fast Absorption! Once again we give you a ground breaking formula that uses our liquid delivery technology to help you recover and grow faster.<\/em><\/p>\n<p><em>Benefits Include:<\/em><br \/>\n<em> &#8211; Excellent for muscle recovery from training<\/em><br \/>\n<em> &#8211; Convenient, fast-acting liquid<\/em><br \/>\n<em> &#8211; Great taste<\/em><br \/>\n<em> &#8211; Uses the same multi-patented pHCD (pH-Controlled Delivery) technology as Liquid Kre-Alklayn EFX&#8221;<\/em><\/p>\n<p>I was idly scanning the &#8220;What&#8217;s New&#8221; list over at bodybuilding.com&#8230;when this one caught my eye. I had to do a double take, because I couldn&#8217;t quite believe what I was seeing.<\/p>\n<p>LIQUID L-GLUTAMINE???!!!<\/p>\n<p>Permit me to explain&#8230;<\/p>\n<p>Back in my research daze, I used to do cell culture experiments. A LOT of cell culture experiments. And in addition to the experiments, I maintained the cell stocks and supplies\u2014including the growth media.<\/p>\n<p>Preparing a bottle of &#8220;complete&#8221; media involved several steps: we started with various basal formulas, which had names like DMEM and RPMI-1640, then added &#8220;standard issue&#8221; stuff like penn\/strep (antibiotics), fetal calf serum and&#8230;<a href=\"http:\/\/www.sigmaaldrich.com\/life-science\/cell-culture\/learning-center\/media-expert\/glutamine.html\" target=\"_blank\" rel=\"noopener\">glutamine<\/a>.<\/p>\n<p>Growing cells need amino acids, of course, but most were included in the basal formula&#8230;excepting glutamine. The glutamine was ALWAYS added separately, just before use.<\/p>\n<p>Why?<\/p>\n<p>Because L-glutamine is notoriously unstable in solution. It slowly, but steadily <a href=\"http:\/\/www.thermofisher.com\/content\/dam\/LifeTech\/migration\/en\/filelibrary\/pdf.par.60035.file.dat\/stability-glutamax-y14475-stblty-glutamax.pdf\" target=\"_blank\" rel=\"noopener\">decomposes to ammonia<\/a> (toxic) and pyroglutamate at room temperature (and more rapidly at incubator temps).<\/p>\n<p>Our lab&#8217;s glutamine was purchased frozen, in small, 100 ml bottles\u2014and it stayed frozen until a bottle was needed. Once thawed, it stayed in the refrigerator for 2\u20133 weeks, max\u2014then was discarded.<\/p>\n<p>So hopefully, you understand my reaction&#8230;Glutamine Elite appears to be free form L-glutamine dissolved in (mostly) water + a few additives, and is being sold unrefrigerated, let alone unfrozen.<\/p>\n<blockquote><p><strong>Active Ingredients<\/strong><\/p>\n<p>L-Glutamine 3000mg<\/p>\n<p>Calories 20g<br \/>\nTotal Carbohydrates 5g<br \/>\nFat 0g<br \/>\nSugars 0g<\/p>\n<p><strong>Inactive Ingredients<\/strong><br \/>\nA Proprietary Oral Delivery System Containing Purified Water, Glycerine, Natural Flavors, Citric Acid, Red Beets, And Potassium Sorbate As A Stabilizer<\/p><\/blockquote>\n<p>This is all that&#8217;s on the product page. Elsewhere on the site, there&#8217;s a certificate of analysis, which is unrevealing w\/respect to shelf stability.<\/p>\n<p>It states on the form that the product is &#8220;heat and cold stable,&#8221; and has a 36 month shelf life, but no proof of either is provided.<\/p>\n<p>This is especially remarkable, since All American claims Glutamine Elite is made using the same pH-controlled delivery techology as &#8220;Liquid Kre-Alkalyn EFX.&#8221;<\/p>\n<p>Kre-Alkalyn EFX is buffered\u2014and presumably has the high (alkaline) pH characteristic of regular Kre-Alkalyn. Yet <a href=\"http:\/\/www.sigmaaldrich.com\/life-science\/cell-culture\/learning-center\/media-expert\/glutamine.html\" target=\"_blank\" rel=\"noopener\">glutamine is LESS stable at high pH<\/a>, not more.<\/p>\n<p>I&#8217;m equally puzzled by the logic behind this supplement. L-Glutamine\u2014in powder form\u2014is a common addition to many bodybuilding stacks. I&#8217;ve yet to hear of any problems with either the powdered free form amino acid or glutamine peptides. So even if the stability of Glutamine Elite was proven, why bother with a liquid? Seems to me that Glutamine Elite is a solution (no pun intended) in search of a problem.<\/p>\n<p>And it&#8217;s a relatively expensive solution at that. One 32 serving bottle sells for close to $20.00 on bodybuilding.com&#8230;at a mere 3 g L-glutamine per serving, this adds up to a paltry 96 grams.<\/p>\n<p>As Paul notes, <a href=\"https:\/\/www.ultimatefatburner.com\/bodybuilding\/l-glutamine-review.html\">L-glutamine can be a useful supplement<\/a>&#8230;but in larger amounts. At the 10\u201315 g he recommends, a bottle would not last long. You could buy 4\u20135 times as much powder for a similar price.<\/p>\n<p>Overall, there are unanswered questions\u2014and potential liabilities\u2014associated with this product. I see no reason to prefer it over other, more conventional offerings, and good reasons to avoid it.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Note: Glutamine Elite is discontinued. &#8220;Lighting Fast Absorption! Once again we give you a ground breaking formula that uses our liquid delivery technology to help you recover and [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[7],"tags":[9,8],"_links":{"self":[{"href":"https:\/\/www.ultimatefatburner.com\/bodybuilding\/wp-json\/wp\/v2\/posts\/63"}],"collection":[{"href":"https:\/\/www.ultimatefatburner.com\/bodybuilding\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.ultimatefatburner.com\/bodybuilding\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.ultimatefatburner.com\/bodybuilding\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ultimatefatburner.com\/bodybuilding\/wp-json\/wp\/v2\/comments?post=63"}],"version-history":[{"count":5,"href":"https:\/\/www.ultimatefatburner.com\/bodybuilding\/wp-json\/wp\/v2\/posts\/63\/revisions"}],"predecessor-version":[{"id":2755,"href":"https:\/\/www.ultimatefatburner.com\/bodybuilding\/wp-json\/wp\/v2\/posts\/63\/revisions\/2755"}],"wp:attachment":[{"href":"https:\/\/www.ultimatefatburner.com\/bodybuilding\/wp-json\/wp\/v2\/media?parent=63"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.ultimatefatburner.com\/bodybuilding\/wp-json\/wp\/v2\/categories?post=63"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.ultimatefatburner.com\/bodybuilding\/wp-json\/wp\/v2\/tags?post=63"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}