{"id":200,"date":"2012-12-17T20:46:36","date_gmt":"2012-12-17T20:46:36","guid":{"rendered":"http:\/\/bodybuilding.ultimatefatburner.com\/?p=200"},"modified":"2015-12-07T11:41:32","modified_gmt":"2015-12-07T16:41:32","slug":"capsiplex-fat-burner-review2","status":"publish","type":"post","link":"https:\/\/www.ultimatefatburner.com\/bodybuilding\/capsiplex-fat-burner-review2.html","title":{"rendered":"Capsiplex Review: What Is Capsiplex? Does It Work?"},"content":{"rendered":"<p>Recently a visitor asked me about <strong>Capsiplex<\/strong>, the red pepper based, &#8220;clinically proven and endorsed by celebrities and doctors&#8221; diet pill everybody is &#8220;raving&#8221; about. Apparently, he couldn&#8217;t find a real review of the product, as all the write ups he found were nothing more than a regurgitation of the product&#8217;s sales pitch made by enthusiastic affiliates eager to earn a commission on referred sales (promoting Capsiplex pays well\u2014<a href=\"https:\/\/moreniche.com\/network\/directory\/health\/capsiplex-affiliate-program\/\" target=\"_blank\" rel=\"noopener\">affiliates earn 30% of sales<\/a>).<\/p>\n<p>He assumed that perhaps this financial conflict of interest was preventing an &#8220;honest&#8221; review from being undertaken. He asked that we do the &#8220;UltimateFatBurner.com&#8221; treatment on Capsiplex.<\/p>\n<p>Of course, he had us at the &#8220;doctor recommended&#8221; and &#8220;celebrity endorsed.&#8221; So yes&#8230; we&#8217;re only too happy to oblige.<\/p>\n<p>So what exactly is Capsiplex?<\/p>\n<p>It&#8217;s a product that contains a combination of 4 ingredients: caffeine (200 mg), capsaicin 33.4 mg (capsaicin is the active component of chili peppers that gives them their heat) 20 mg of niacin (a B Vitamin), and 5 mg Bioperine (a proprietary pepper extract added to supplements to improve the bioavailability of the various ingredients).<\/p>\n<p>The first thing you notice when you check out Capsiplex online at the official web site, is that there&#8217;s a lot of talk about science, and how Capsiplex is one of the few supplements actually backed by any&#8230;.<\/p>\n<p>&#8220;The unique Capsiplex formula is backed by 30+ years of research, studies and human trials.&#8221;<\/p>\n<p>There is also much ado about a clinical study performed at the University of Oklahoma, which was apparently double blind, placebo controlled, randomized, etc, etc.<\/p>\n<p>But despite all the &#8220;hullabaloo&#8221; made about this study by the retailer and its legions of affiliates, it doesn&#8217;t seem to be published anywhere (and the retailers aren&#8217;t providing a link or a PDF so we can verify the amazing results for ourselves). After some digging, I found out why&#8230;<\/p>\n<p>The actual study <strong><em>wasn&#8217;t<\/em><\/strong> performed on Capsiplex. No, it was performed on <a href=\"http:\/\/:www.omniactives.com\/products\/capsimax\/capsimax_plus.html\">OmniActive&#8217;s Capsimax Plus<\/a>. Capsiplex appears to be a &#8220;rebranded&#8221; Capsimax Plus (it appears that Capsimax Plus is the actual, trademarked ingredient used. Later, when Dr. Karen Vieira is introduced, her &#8220;endorsement&#8221; of Capsiplex seems to verify this; it mentions Capsimax 4 times in a row).<\/p>\n<p>Ooops.<\/p>\n<p>And there are two published studies available; <a href=\"http:\/\/www.lipidworld.com\/content\/9\/1\/72\" target=\"_blank\" rel=\"noopener\">this first one<\/a>\u2014funded by OmniActive itself and performed on 20 exercise-trained men and women\u2014demonstrated supplementing with Capsimax increases plasma free fatty acids, which in essence &#8220;suggests&#8221; this product may aid in the loss of bodyfat (<a href=\"http:\/\/www.lipidworld.com\/content\/9\/1\/72\" target=\"_blank\" rel=\"noopener\">read the &#8220;discussion&#8221; element of the study<\/a> for more on this).<\/p>\n<p>There&#8217;s nothing particularly revolutionary about this; it&#8217;s consistent with what <a href=\"http:\/\/www.jissn.com\/content\/6\/1\/15\" target=\"_blank\" rel=\"noopener\">we already know about red pepper and capsaicin<\/a>. Caffeine too, has well established, albeit mild, metabolism-elevating characteristics (see <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/2912010?ordinalpos=1&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DiscoveryPanel.Pubmed_Discovery_RA&amp;linkpos=1&amp;log$=relatedarticles&amp;logdbfrom=pubmed\" target=\"_blank\" rel=\"noopener\">Am J Clin Nutr. 1989 Jan;49(1):44-50<\/a>, <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/7369170?ordinalpos=1&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DiscoveryPanel.Pubmed_Discovery_RA&amp;linkpos=2&amp;log$=relatedarticles&amp;logdbfrom=pubmed\" target=\"_blank\" rel=\"noopener\">Am J Clin Nutr. 1980 May;33(5):989-97<\/a>).<\/p>\n<p>The second, much-ballyhooed study\u2014<a href=\"http:\/\/www.jissn.com\/content\/6\/1\/15\" target=\"_blank\" rel=\"noopener\">the one performed at the University of Oklahoma<\/a>\u2014didn&#8217;t even address energy metabolism and calorie burn. No, it was on studying cycling time to exhaustion and muscular strength and it demonstrated <a href=\"http:\/\/www.jissn.com\/content\/6\/1\/15\" target=\"_blank\" rel=\"noopener\">no effects<\/a>.<\/p>\n<p>But what about the claims on the web site?<\/p>\n<p>What about the study that showed <strong>278 more calories were burned before, during and after exercise compared to placebo? <\/strong>(The ad copy claims you can burn 278 more calories per day; that&#8217;s based on the assumption you&#8217;re exercising vigorously every day; otherwise, this claim is not applicable, regardless of the authenticity of the science behind it).<\/p>\n<p>Apparently this is an <a href=\"http:\/\/www.naturalproductsinsider.com\/articles\/2009\/08\/thermogenics-turn-up-the-heat-in-weight-loss.aspx?pg=3\" target=\"_blank\" rel=\"noopener\">unpublished study<\/a>.<\/p>\n<p>That&#8217;s right; it&#8217;s not published in a peer reviewed journal, and therefore not available for us (or anyone else for that matter) to review, critique, or evaluate. We have nothing but the retailer&#8217;s word to go on for this. And since the study results were\u00a0discussed <a href=\"http:\/\/www.naturalproductsinsider.com\/articles\/2009\/08\/thermogenics-turn-up-the-heat-in-weight-loss.aspx?pg=3\" target=\"_blank\" rel=\"noopener\">in a 2009 trade industry article<\/a> it&#8217;s a bit odd that it hasn&#8217;t seen the light of day in some journal, somewhere. That is, of course, unless there may be some details (or lack thereof) that would call the desired conclusion into question.<\/p>\n<p>Ooops.<\/p>\n<p>The remainder of studies referenced were not performed on either the Capsiplex or Capsimax formulas; they deal with studies performed with high doses of red pepper (anywhere from 3-10 grams and more; see study abstracts <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/10743483\" target=\"_blank\" rel=\"noopener\">here<\/a>, <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/8926537\" target=\"_blank\" rel=\"noopener\">here<\/a> and <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/11242488\" target=\"_blank\" rel=\"noopener\">here<\/a> as examples).<\/p>\n<p>Red pepper extracts <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/15611784\" target=\"_blank\" rel=\"noopener\">also seem to help with satiety<\/a> and possibly a reduced energy\/fat intake, although studies validating this last point indicate an <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/15182402\" target=\"_blank\" rel=\"noopener\">adherence to the &#8220;maximum tolerable dose&#8221; was a necessity<\/a>.<\/p>\n<p>Nonetheless, the argument here is <strong>not<\/strong> that appropriately dosed red-pepper\/capsaicin supplements can&#8217;t help (especially when they are stacked with caffeine).<\/p>\n<p>What needs to be put into context is <strong><em>just how much they can help<\/em><\/strong>.<\/p>\n<p>Our scientific and technical advisor <a href=\"https:\/\/www.ultimatefatburner.com\/about-us.html\">Elissa<\/a> put it this way&#8230;<\/p>\n<p>&#8220;It&#8217;s like getting a $50 discount on a Cadillac. Measureable and statistically significant, but overall it hardly makes a difference.&#8221;<\/p>\n<p>What&#8217;s that worth to you, exactly?<\/p>\n<p>Since Capsiplex is shipped from the UK, it sells for 34.25 Euros plus shipping (approximately $48 US + $16 shipping to North America).<\/p>\n<p>We&#8217;d argue that&#8217;s pretty expensive, especially when you can buy the original <a href=\"http:\/\/www.swansonvitamins.com\/SWD059\/ItemDetail?n=0\" target=\"_blank\" rel=\"noopener\">Capsimax formula\u2014the formula the studies were actually performed on\u2014for just over $10 at Swanson vitamins<\/a><\/p>\n<p>At this price we say; go ahead and try it if you want. Just don&#8217;t expect miracles. There is absolutely nothing here to warrant a $64 expenditure, however.<\/p>\n<blockquote><p><strong>What about the &#8220;doctor recommended&#8221; claim?<\/strong><br \/>\nYes, Capsiplex appears to be &#8220;doctor&#8221; recommended. Sort of. Let me explain&#8230;<\/p>\n<p>Karen Vieira has a Ph.D. in Biomedical Sciences. So yes, it&#8217;s perfectly acceptable to call her &#8220;doctor.&#8221; However, she is not a medical doctor, as is implied by the Capsiplex advertising. As our scientific and technical advisor <a href=\"https:\/\/www.ultimatefatburner.com\/about-us.html\">Elissa<\/a> explains&#8230;<\/p>\n<p>Ph.D.&#8217;s merit the title of doctor, but when it comes to\u00a0public documents, it&#8217;s considered proper professional practice to make sure that distinctions are clearly communicated. Thus, my &#8220;Superfruits&#8221; book wasn&#8217;t written by &#8220;Dr. Paul Gross&#8221; &#8211; it was written by &#8220;Paul Gross, Ph.D.&#8221; Likewise, &#8220;Dr. Oz&#8217;s&#8221; book, &#8220;You, The Owners Manual&#8221; wasn&#8217;t written by &#8220;Dr. Oz&#8221; &#8211; it was written by &#8220;Mehmet C. Oz, M.D.&#8221;<\/p>\n<p>This is important, since, conceivably, you could pass off someone with a doctorate in English as a &#8220;doctor&#8221; for the purposes of advertising&#8230; which is obviously deceptive. One is &#8220;doctor&#8221; to one&#8217;s students and peers, but not when it comes to presenting yourself to the general public. <a href=\"https:\/\/www.ftc.gov\/news-events\/press-releases\/2004\/06\/ads-various-diet-supplements-and-topical-gels-dont-cut-fat-says\" target=\"_blank\" rel=\"noopener\">The FTC has called people on this before<\/a>.<\/p>\n<p>To be a professional means being precise, so as not to mislead. Thus, referring to Karen Vieira as &#8220;Dr. Vieira&#8221; isn&#8217;t &#8220;wrong&#8221; per se (she holds a legitimate\u00a0doctorate after all), but the failure to clarify is.<\/p>\n<p><strong>Sidenote:<\/strong> Karen Vieira also owns a business called &#8220;TheMedWriters.com&#8221;, which writes supplement sales copy, compiles product formulas and so on.<\/p>\n<p>And what about the &#8220;celebrity endorsement&#8221; claims? Impossible to verify, and meaningless even if they are genuine, as personal testimonials are anecdotal\u2014regardless from whom they come.<\/p><\/blockquote>\n","protected":false},"excerpt":{"rendered":"<p>Recently a visitor asked me about Capsiplex, the red pepper based, &#8220;clinically proven and endorsed by celebrities and doctors&#8221; diet pill everybody is &#8220;raving&#8221; about. Apparently, he couldn&#8217;t [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[32],"tags":[38],"_links":{"self":[{"href":"https:\/\/www.ultimatefatburner.com\/bodybuilding\/wp-json\/wp\/v2\/posts\/200"}],"collection":[{"href":"https:\/\/www.ultimatefatburner.com\/bodybuilding\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.ultimatefatburner.com\/bodybuilding\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.ultimatefatburner.com\/bodybuilding\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ultimatefatburner.com\/bodybuilding\/wp-json\/wp\/v2\/comments?post=200"}],"version-history":[{"count":5,"href":"https:\/\/www.ultimatefatburner.com\/bodybuilding\/wp-json\/wp\/v2\/posts\/200\/revisions"}],"predecessor-version":[{"id":2800,"href":"https:\/\/www.ultimatefatburner.com\/bodybuilding\/wp-json\/wp\/v2\/posts\/200\/revisions\/2800"}],"wp:attachment":[{"href":"https:\/\/www.ultimatefatburner.com\/bodybuilding\/wp-json\/wp\/v2\/media?parent=200"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.ultimatefatburner.com\/bodybuilding\/wp-json\/wp\/v2\/categories?post=200"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.ultimatefatburner.com\/bodybuilding\/wp-json\/wp\/v2\/tags?post=200"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}