{"id":107,"date":"2009-01-17T19:48:28","date_gmt":"2009-01-17T19:48:28","guid":{"rendered":"http:\/\/bodybuilding.ultimatefatburner.com\/?p=107"},"modified":"2015-12-03T11:12:43","modified_gmt":"2015-12-03T16:12:43","slug":"ast-anabolic-rush-review","status":"publish","type":"post","link":"https:\/\/www.ultimatefatburner.com\/bodybuilding\/ast-anabolic-rush-review.html","title":{"rendered":"Review: AST&#8217;s Anabolic Rush Nitric Oxide Supplement"},"content":{"rendered":"<p><strong>Note: Anabolic Rush has been discontinued.<\/strong><\/p>\n<p><b>Anabolic Rush<\/b> is a new state of the art muscle-building and energizing formula that uses innovative breakthroughs in nutrient design and delivery technology to maximize muscle cell volume, mind-muscle energy, androgen receptor amplification, creatine absorption, muscle endurance and nitrogen retention&#8230;Anabolic Rush is to muscle growth what nitro-methane is to horsepower. There are plenty of supplements on the market but there&#8217;s nothing like Anabolic Rush.<\/p>\n<p>This is part of the intro to &#8220;Anabolic Rush,&#8221; AST&#8217;s new pre-workout, nitric-oxide (NO) supplement. As common as NO-boosters are these days, I was still a bit surprised to see this one. I&#8217;m pretty familiar with AST&#8217;s product line, which features basic, no-nonsense supplements, such as micronized creatine monohydrate, protein powder, bars, a multivitamin, CLA, beta-alanine, L-glutamine, etc. A complex supplement like Anabolic Rush seems&#8230;I dunno, kinda out of character.<\/p>\n<p>In more ways than one&#8230; I also recall a time\u2014not so very long ago\u2014when the company wasn&#8217;t too keen on nitric oxide (NO) supplements. For example, an article by Paul Cribb, AST&#8217;s Director of Research, called &#8220;Nitric Oxide Supplements\u2014Big Claims\u2014Zero Science: NO 2 ways about it&#8221; can still be found in various places on the internet.<\/p>\n<p>Well, that was then and this is now, I suppose. Looks like AST&#8217;s changed its mind about complicated formulas&#8230;and nitric oxide supplements. Anabolic Rush is the company&#8217;s answer to <a href=\"https:\/\/www.ultimatefatburner.com\/bodybuilding\/BSN-NO-Xplode.html\">NO-Xplode<\/a>, <a href=\"https:\/\/www.ultimatefatburner.com\/bodybuilding\/gaspari-superpump-250.html\">SuperPump 250<\/a>, <a href=\"https:\/\/www.ultimatefatburner.com\/bodybuilding\/vpx-no-shotgun-review.html\">NO Shotgun<\/a> and other popular NO-boosters.<\/p>\n<p>This is obvious by looking at the label&#8230;<\/p>\n<blockquote><p><strong>Anabolic Rush\u2122 Proprietary Substrate Matrix 23,935mg<\/strong><\/p>\n<p><strong>C5MX\u2122 &#8211; Creatine Matrix<\/strong><br \/>\nCreatine Monohydrate, Creatine Alpha Keto Glutarate, TriCreatine Malate, Creatine Citrate, Magnesium Creatine Chelate.<br \/>\n<strong>MCXC\u2122 &#8211; Muscle Cell Xpander Complex\u2122<\/strong><br \/>\nL-Glutamine, L-Leucine, L-Isoleucine, L-Valine, Taurine, Methionine, Glycine, Glycocyamine, Manganese, Vanadium Chelate<br \/>\n<strong>Androgen Receptor Amplifier\u2122<\/strong><br \/>\nCarnitine L-Tartrate (LCLT), Ascorbic Acid (Vitamin C), Pyridoxine HCL (B6), Zinc, Cyanocobalamin (B12)<br \/>\n<strong>Mind-Muscle Energy Stimulator\u2122<\/strong><br \/>\nL-Tyrosine, L-Phenylalanine, Extenergen (Caffeine, Phenylethylamine HCL, Glucuronolactone, Picamilon, Nettle Root Extract, Magnolia Extract, Yohimbine HCL, Inositol Niacinate, Thiamine Disulfide), Trimethylglycine (TMG), Vinpocetine, Vincamine, Vinburnine<br \/>\n<strong>Nitric-Rush\u2122<\/strong><br \/>\nArginine AKG, Citruline Malate, Arginine, Malic Acid<br \/>\n<strong>RepXtra\u2122<\/strong><br \/>\nBeta-X\u2122-Patented Beta-Alanine<br \/>\n<strong>Hydro-InFuse\u2122 &#8211; Sustained Electrolyte Complex\u2122<\/strong><br \/>\nMagnesium Phosphate, Di-Sodium Phosphate, Di-Potassium Phosphate, Di-Calcium Phosphate<\/p><\/blockquote>\n<p>It&#8217;s all there: the arginine salts, creatine, electrolytes and nootropics.<\/p>\n<p>But the more, the merrier&#8230;and I like this genre of supplements, as they certainly help with focus, concentration and performance in the gym. So let&#8217;s take a closer look at each blend, and see how Anabolic Rush measures up.<\/p>\n<p><strong>C5MX\u2122<\/strong>: This is a blend of 5 different creatine forms. The first, of course, is an old friend, <a href=\"https:\/\/www.ultimatefatburner.com\/bodybuilding\/creatine-monohydrate.html\">creatine monohydrate<\/a>. Most of the others are also well known, and\u2014in the case of <a href=\"http:\/\/www.jissn.com\/content\/4\/1\/17\" target=\"_blank\" rel=\"noopener\">creatine citrate<\/a> and <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/15142029\" target=\"_blank\" rel=\"noopener\">magnesium creatine chelate<\/a>\u2014there&#8217;s even a little research available. Two points, however:<\/p>\n<ol>\n<li>there&#8217;s exactly zero published data to indicate that ANY alternative creatine form gives results superior to creatine monohydrate; and<\/li>\n<li>there&#8217;s exactly zero data to indicate that consuming multiple forms of creatine gives results superior to consuming a single form.<\/li>\n<\/ol>\n<p>I feel like a broken record on these two points, but whatever&#8230;These days, EVERYONE&#8217;s doing this, so I can hardly blame AST for falling into line.<\/p>\n<p><strong>MCXC\u2122<\/strong>: The &#8220;Muscle Cell Xpander Complex&#8221; contains the <a href=\"https:\/\/www.ultimatefatburner.com\/bodybuilding\/BCAAs-branched-chain-amino-acids.html\">branched chain amino acid<\/a>, leucine, which serves an important function as an initiator of muscle protein synthesis. The MCXC blend also contains several compounds known to modulate blood sugar and insulin: <a href=\"https:\/\/www.ultimatefatburner.com\/bodybuilding\/taurine-review.html\">taurine<\/a> (which also has antioxidant effects), <a href=\"https:\/\/www.ultimatefatburner.com\/bodybuilding\/l-glutamine-review.html\">glutamine<\/a>, <a href=\"http:\/\/ajcn.nutrition.org\/content\/76\/6\/1302.full\" target=\"_blank\" rel=\"noopener\">glycine<\/a>, <a href=\"http:\/\/lpi.oregonstate.edu\/mic\/minerals\/manganese\" target=\"_blank\" rel=\"noopener\">manganese<\/a> and <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/12831353\" target=\"_blank\" rel=\"noopener\">vanadium<\/a>. Glycocyamine may as well, but there&#8217;s no human data to justify its use for this purpose.<\/p>\n<p><strong>Androgen Receptor Amplifier\u2122<\/strong>: The primary ingredient in this blend is L-carnitine, which was shown to <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/16826026\" target=\"_blank\" rel=\"noopener\">enhance androgen receptors in exercising men<\/a> following a short term (21 day) feeding experiment. <a href=\"https:\/\/www.ultimatefatburner.com\/vitamins\/vitamin-c.html\">Vitamin C<\/a>, <a href=\"http:\/\/lpi.oregonstate.edu\/mic\/vitamins\/vitamin-B6\" target=\"_blank\" rel=\"noopener\">Vitamin B6<\/a>, <a href=\"https:\/\/www.ultimatefatburner.com\/vitamins\/zinc-review.html\">zinc<\/a> and <a href=\"https:\/\/www.ultimatefatburner.com\/vitamins\/vitamin-b12.html\">Vitamin B12<\/a> are all nutrients identified as important for male fertility and reproductive function.<\/p>\n<p><strong>Mind-Muscle Energy Stimulator\u2122:<\/strong> This is a pretty complex and diverse blend. Here&#8217;s the breakdown:<\/p>\n<ul>\n<li><strong>L-Tyrosine:<\/strong> a non-essential amino acid synthesized from phenylalanine. <a href=\"https:\/\/www.ultimatefatburner.com\/l-tyrosine.html\">Tyrosine<\/a> is a precursor for several important physiological compounds, including thyroid hormone(s) and the catecholamine neurotransmitters, dopamine, norepinephrine and epinephrine. Tyrosine administration has been shown to improve mood and performance under <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17585971?ordinalpos=11&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum\" target=\"_blank\" rel=\"noopener\">environmental<\/a> and <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/1599383?ordinalpos=4&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum\" target=\"_blank\" rel=\"noopener\">physical stress<\/a>.<\/li>\n<li><strong>L-Phenylalanine:<\/strong> an essential amino acid and precursor to both tyrosine and phenethylamine (PEA).<\/li>\n<li><strong>Caffeine:<\/strong> a well-known stimulant found naturally in coffee, tea, guarana and chocolate.<\/li>\n<li><strong>Phenethylamine HCl (PEA):<\/strong> the reputed &#8220;love drug&#8221; from chocolate, although its effects are limited as it&#8217;s rapidly broken down before it reaches the brain.<\/li>\n<li><strong>Glucuronolactone:<\/strong> a naturally-occurring metabolite of glucose. Glucuronolactone is used in energy drinks as well as some pre-workout supplements as an energy booster. It&#8217;s also sold in bulk powder form. There are no studies on glucuronolactone that validate its use for enhancing mood or energy. Most people using the bulk powder, give it a thumbs up, however. I&#8217;ve tried it myself: it seems to give a mild boost.<\/li>\n<li><strong>Picamilon:<\/strong> a niacin-bound derivative of the inhibitory neurotransmitter <a href=\"https:\/\/www.ultimatefatburner.com\/glossary\/gaba\/\">GABA<\/a> (it&#8217;s also spelled pikamilon). Picamilon has been extensively investigated in Russia, but little researched in the West. It allegedly increases cerebral blood flow and induces a state of relaxation, without drowsiness.<\/li>\n<li><strong>Nettle Root Extract:<\/strong> &#8220;Stinging Nettle&#8221; (<a href=\"https:\/\/www.ultimatefatburner.com\/glossary\/urtica-dioica\/\">Urtica dioica<\/a>) has been used as a traditional herbal remedy for centuries. Stinging nettle extracts are also used in modern medicine as <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/17509841?ordinalpos=1&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum\" target=\"_blank\" rel=\"noopener\">an alternative therapy for benign prostatic hyperplasia<\/a> (BPH, or enlarged prostate). In vitro (cell culture) experiments have shown that <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/9434605?ordinalpos=1&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVAbstractPlus\" target=\"_blank\" rel=\"noopener\">Urtica extracts can inhibit SHBG<\/a> (sex hormone binding globulin)\u2014a protein that binds to testosterone and limits its bioavailability.<\/li>\n<li><strong>Magnolia Extract:<\/strong> animal (and limited human) experiments have shown magnolia extracts or honokiol, the active ingredient, are <a href=\"http:\/\/www.nutritionj.com\/content\/7\/1\/11\" target=\"_blank\" rel=\"noopener\">effective for reducing responses to stress<\/a>.<\/li>\n<li><strong>Yohimbine HCl:<\/strong> a fat loss compound that\u00a0stimulates lipolysis by increasing <a href=\"https:\/\/thinksteroids.com\/articles\/fat-loss-yohimbine-02\/\" target=\"_blank\" rel=\"noopener\">blood flow in adipose tissue and\u00a0blocking the activation of a <sub>2<\/sub>-adrenoceptors<\/a> on fat cells\u2026although it <a href=\"http:\/\/www.thinkmuscle.com\/articles\/haycock\/women-and-lower-body-fat.htm\" target=\"_blank\" rel=\"noopener\">works better in theory than in fact<\/a>. It&#8217;s also sold as a <a href=\"https:\/\/www.nlm.nih.gov\/medlineplus\/druginfo\/natural\/759.html\" target=\"_blank\" rel=\"noopener\">treatment for male impotence<\/a>.<\/li>\n<li><strong>Inositol Niacinate:<\/strong> &#8220;Flush free&#8221; niacin used as to <a href=\"http:\/\/www.drugs.com\/cdi\/inositol-niacinate.html\" target=\"_blank\" rel=\"noopener\">reduce blood lipids and improve circulation<\/a>.<\/li>\n<li><strong>Thiamine Disulfide:<\/strong> an oxidized dimer of the B-vitamin,<a href=\"https:\/\/www.ultimatefatburner.com\/vitamins\/vitamin-b1-thiamin.html\"> thiamine<\/a>.<\/li>\n<li><strong>Trimethylglycine:<\/strong> also known as betaine. Betaine is a &#8220;methyl donor&#8221; that can <a href=\"http:\/\/jn.nutrition.org\/content\/133\/12\/4135.full\" target=\"_blank\" rel=\"noopener\">help reduce plasma homocysteine<\/a>\u2014a risk factor for cardiovascular disease. It may also <a href=\"http:\/\/umm.edu\/health\/medical\/altmed\/supplement\/betaine\" target=\"_blank\" rel=\"noopener\">protect the liver against fatty liver disease<\/a>.<\/li>\n<li><strong>Vinpocetine\/Vincamine\/Vinburnine:<\/strong> alkaloids derived from periwinkle that affect cerebral blood flow, memory and learning.<\/li>\n<\/ul>\n<p>I&#8217;ll say it up front: this is an odd-looking blend. It&#8217;s overly complicated, which always raises questions about dose. In addition, some of the ingredients are questionable: PEA breaks down too quickly to be of any real use; whereas yohimbine, nettle root extract and betaine\u2014while useful in other contexts\u2014just don&#8217;t have much of an impact on mood, focus or concentration.<\/p>\n<p><strong>Nitric-Rush\u2122<\/strong>: Arginine and <a href=\"https:\/\/www.ultimatefatburner.com\/bodybuilding\/Citrulline-nitric-oxide.html\">citrulline<\/a> are &#8220;standard issue&#8221; compounds for any <a href=\"https:\/\/www.ultimatefatburner.com\/bodybuilding\/no2-nitric-oxide.html\">NO booster<\/a>. Arginine\/arginine salts are used to produce nitric oxide, and <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2291275\/?tool=pubmed\" target=\"_blank\" rel=\"noopener\">citrulline serves as an alternate source of arginine<\/a>.<\/p>\n<p><strong>RepXtra\u2122<\/strong>: Beta-alanine is one-half of the naturally-occurring dipeptide carnosine (beta-alanyl-l-histidine), which\u2014among other functions\u2014helps to buffer hydrogen ions produced during intense muscular contractions. Beta-alanine supplementation has been shown to <a href=\"http:\/\/web.archive.org\/web\/20101012160846\/http:\/\/www.joseantoniophd.com\/website\/articles.php?id=32\" target=\"_blank\" rel=\"noopener\">increase storage of muscle carnosine<\/a>, <a href=\"http:\/\/jap.physiology.org\/content\/103\/5\/1736.abstract\" target=\"_blank\" rel=\"noopener\">reduce muscular fatigue<\/a>, and <a href=\"http:\/\/link.springer.com\/article\/10.1007%2Fs00726-006-0364-4\" target=\"_blank\" rel=\"noopener\">improve high intensity athletic performance<\/a>.<\/p>\n<p><strong>Hydro-InFuse\u2122 \u2014 Sustained Electrolyte Complex\u2122<\/strong>: phosphate salts serve a dual purpose: to replace electrolytes lost in sweat, and as sources of phosphate for ATP production.<\/p>\n<p>So there we have it&#8230;<\/p>\n<p>On paper, Anabolic Rush resembles a typical NO-booster that should be interchangeable with other popular brands.<\/p>\n<p>But the proof of that lies in the testing.<\/p>\n<p>With that in mind, I put in my order and gave it a whirl.<\/p>\n<p>The verdict? Uneven.<\/p>\n<p>This also surprised me, as it had been at least a month since I&#8217;d used ANY NO product, and was expecting a pretty good rush.<\/p>\n<p>I didn&#8217;t get one, however, even with two full scoops. It did make me feel more alert\u2014like I&#8217;d had a cup of coffee\u2014and produced a modest pump&#8230;but that was it.<\/p>\n<p>Same deal over the next couple of workouts. The only time I really felt this supplement had an impact was at bedtime: I ended up tossing and turning for 2+ hours before finally dropping off to sleep. Since I need my sleep, I decided to cut the experiment short.<\/p>\n<p>Anabolic Rush &#8220;works,&#8221; I suppose, but the experience wasn&#8217;t on the same level as other popular NO-boosters I&#8217;ve tried\u2014there&#8217;s just something missing. I think it comes back to the &#8220;Mind-Muscle Energy Stimulator&#8221; complex. As noted above, there are potential issues with large, overly complicated blends. Personally, I&#8217;d prefer to see a blend with a few, well-chosen ingredients, vs. one with a lot of (potentially underdosed) compounds jumbled together.<\/p>\n<p>In fairness, Anabolic Rush also contains ingredients that would be beneficial over longer-term use, such as creatine, beta-alanine and carnitine. In addition, it tastes pretty good and dissolves well.<\/p>\n<p>In searching for reasons to prefer this product over others, however, these &#8220;pluses&#8221; aren&#8217;t compelling&#8230;creatine, beta-alanine and carnitine are easily obtained from other sources; and\u2014like a lot of gym rats\u2014I&#8217;ll happily trade taste for results. It&#8217;s the laser-beam focus and pump that I&#8217;m after, and\u2014unfortunately\u2014this is exactly where Anabolic Rush falls a bit flat.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Note: Anabolic Rush has been discontinued. Anabolic Rush is a new state of the art muscle-building and energizing formula that uses innovative breakthroughs in nutrient design and delivery [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[14],"tags":[15,16],"_links":{"self":[{"href":"https:\/\/www.ultimatefatburner.com\/bodybuilding\/wp-json\/wp\/v2\/posts\/107"}],"collection":[{"href":"https:\/\/www.ultimatefatburner.com\/bodybuilding\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.ultimatefatburner.com\/bodybuilding\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.ultimatefatburner.com\/bodybuilding\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ultimatefatburner.com\/bodybuilding\/wp-json\/wp\/v2\/comments?post=107"}],"version-history":[{"count":7,"href":"https:\/\/www.ultimatefatburner.com\/bodybuilding\/wp-json\/wp\/v2\/posts\/107\/revisions"}],"predecessor-version":[{"id":2768,"href":"https:\/\/www.ultimatefatburner.com\/bodybuilding\/wp-json\/wp\/v2\/posts\/107\/revisions\/2768"}],"wp:attachment":[{"href":"https:\/\/www.ultimatefatburner.com\/bodybuilding\/wp-json\/wp\/v2\/media?parent=107"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.ultimatefatburner.com\/bodybuilding\/wp-json\/wp\/v2\/categories?post=107"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.ultimatefatburner.com\/bodybuilding\/wp-json\/wp\/v2\/tags?post=107"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}