A natural anti-inflammatory compound derived from white willow bark (Salix alba). Salicin is chemically similar to aspirin, and has a similar action.
White willow bark extracts standardized for salicin were typically added to ephedra-based fat burners designed to be “all natural” versions of the well-known “ECA” stack (ephedrine, caffeine, aspririn – see Paul’s Xenadrine RFA review for one example). Theoretically, aspirin/salicin works synergistically with ephedrine/caffeine to enhance lipolysis, but there is less research to back this up (and the “EC” stack is quite effective without it).
Salicin-containing extracts are also added to “ephedra-free” fat burners, but there is no evidence it provides any benefits.