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3,3′-Diiodo-L-Thyronine

Also known as 3,3′ T2.  A breakdown metabolite of the active (T3) thyroid hormone, 3,3′,5-triiodo-L-thyronine.  It’s included in some weight loss supplements as a “thyromimetic” compound, although there is no human data to support its use for this purpose.  There is limited animal data that demonstrates it can increase metabolic rate and energy expenditure, but the 3,3′-diiodo-l-thyronine was...

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4-Hydroxyandrostenedione

See Formestane.

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1-Androsterone

Androsterone (ADT)  is a testosterone metabolite that is secreted in sweat and excreted in urine.  It’s a reputed pheromone and weak androgen.  1-Androsterone has a double bond at C-1, and is alleged to be a prohormone for 1-testosterone, a potent anabolic steroid and Schedule III controlled substance.  Unlike the now-banned prohormones, however, more than one enzymatic step is required to convert 1-androsterone to the target...

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Cis-9,10-Octadecenoamide

Also known as oleamide.  A naturally-occurring derivative of oleic acid (a monounsaturated fatty acid) that induces sleep.  Research is ongoing, but in-vitro and rodent experiments indicate it may have other functions as well.  For example, it may have anxiolytic (anxiety-reducing) and anti-convulsant activities.  Oleamide derivatives also inhibit the metastasis of cancer cells...

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4-Hydroxyphenylalanine

See L-Tyrosine.

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1-Phenyl-2-Amino-Athan

Also known as beta-phenethylamine or 2-phenethylamine.  PEA is a biogenic amine synthesized from the amino acid phenylalanine.  Although it’s found in a number of foods, chocolate is the best-known source of dietary PEA.  PEA was once thought to be the reason people are “chocoholics (due to its mood-elevating properties); but it’s too rapidly metabolized to be very effective. Phenethylamine is the...

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